I keep going back and forth between metering with my dome facing the camera versus the key light, and was hoping some of you may be able to provide a bit of insight.
For my measurebator setup, I used a Seconic L-358 with no exposure compensation dialed in and the dome extended, an Elinchrom RX 600, Canon 5D (set to Neutral with all settings set to zero & shooting RAW), Canon 24-70 f2.8 L, and I was shooting a Gretag Macbeth 24 square color checker chart.
The RX 600 was placed at a 45° angle to the chart and I did a separate white balance, for the difference in exposure, for each set of shots -- dome facing the camera, or facing the key light. For each set of three shots, the first shot was exactly how the chart was metered, with the second and third shots being one third stop overexposed and one third stop underexposed.
Since I shoot with Canon I decided to use the DPP software that shipped with the camera (again, all setting set to zero). I thought it would be helpful to include the RGB values from the white patch (since shooting digital I don't want to blow out my highlights), and middle gray (umm, dunno why
). So I'll start with those values from the "properly" exposed images and include more if anyone thinks it would be helpful.
Properly exposed image, with dome pointed toward the key light.
White patch RGB = 236, 235, 235
Middle gray patch RGB = 129, 129, 128
Properly exposed image, with dome pointed into the lens.
White patch RGB = 244, 244, 243
Middle gray patch RGB = 142, 143, 142
Personally, I learned to meter with the dome pointing into the lens which in this case seems to give me about perfect exposure. However, I know several very accomplished photographers who meter with the dome pointed toward the key light in order to avoid blowing out highlights with digital capture.
I'd really appreciate any thoughts about my little experiment (I'm no Robert... LOL) as well as how you meter, and why.
Edit: I didn't make it clear that I'm most interested in metering for my final taking aperture for proper exposure, regardless of the number of lights used. I added this because we could go into a lengthy discussion about metering for ratios, as well, which I'd really enjoy in another discussion. But we can certainly include it here if it would be of benefit. 



