I did a quick comparison of the photozone test results for the of the Zeiss 21 and the Canon 16-35 (at 20mm). (The two lenses are pretty much equivalent in price.) Three things impressed me:
1. Distortion is about the same for the two lenses. They measured 1.7% on the Zeiss, and 1.6% on the Canon (at 20mm).
2. Wide open, the Zeiss hold its sharpness very well, even to the extreme corners, and the Canon is relatively weak in this regard. But, this comes at the expense of some very severe vignetting: 2.5EV for the Zeiss vs 1.6EV for the Canon.
3. At the 'sweet spot' of f5.6, the resolution numbers for both the Zeiss and the Canon zoom (at 20mm) are impressive. They both have very good numbers from the image center to the extreme corners. By f5.6, vignetting is reasonably well-controlled for both lenses - 0.92EV for the Zeiss, and 0.82EV for the Canon (at 20mm).
With the Canon, you get AF, and the versatility of being able to go wider or longer than 21mm. At moderate apertures, it doesn't seem that the Zeiss has any advantage over the Canon zoom (when you set the zoom to 20mm). The only advantage to the Zeiss seems to me to be the superior edge-to-edge sharpness at f2.8 (which is counterbalanced somewhat by its significant vignetting).
Al