The camera settings act like a preset in DPP for the Raw converter. They don't change the Raw data and can be freely tampered with until you Convert and Save.
Sharpening in your Raw converter is partly a matter of taste but with a concern to bear in mind. If you plan to process your Raw and then Convert to a final output (jpeg, print, etc) then sharpen it as much as you like, making sure to examine it at various levels of enlargement to ensure that something doesn't look garish or that you don't get artifacts that will bite you. Then, be happy.
However, if the image you are working on is going to be sent to Photoshop or another full-featured editor, then there is good reason to only apply a minimal amount of "capture sharpening" to just bring the needed bits of detail/contrast out of the naturally somewhat soft Raw capture, and then in Photoshop apply its more exacting sharpening methods where you can at the very least apply a mask and selectively apply sharpening and/or noise reduction.
Since I don't normally resort to Photoshop for my images unless I have a specific special goal in mind, I work with my sharpening and NR tools in Raw to, as much as I can, "get it right". Sometimes a scene/subject can take more, sometimes less -- just try to get a feel of things as your go.