Lowepro Runner 450 or Flipside 400/500

I am having a hard time finding the right Backpack for my gear. (Sub $200 and comfortable to wear) I do alot of traveling and would need the bag to fit with no problems either in the overhead bin of a standard MD80 or bigger aircraft, or under the seat. Most of the gear I will be lugging around:

Gripped 5D Mark II
Gripped Rebel
Sigma 150-500
Sigma 50mm
Canon 24-105
Canon 70-200 2.8
Canon 24-70
580EX II
And some chargers/cables/batter​ies etc.

Would be nice to also carry my laptop in this bag, but don't think the Flipside has the capability for that, so I can do without.
I don't want to have a bag that is too big for my gear or too small, and all the local stores I have been to don't carry these bags and it is hard to decide by looking at online pictures.

Any input would be appreciated.

Hi, I was looking at the same exact 2 bags just a 2 weeks ago. Both are great bags!! Went to B&H and look at them both before purchasing. I went with the the pro runner over the flipside for 2 reasons, first it has AW cover to protect from water, sand or dust, and second it hold s a laptop. So if you don't need either of those 2 features, the flipside is a great bag too.

Well, I ordered the Pro Runner 450 AW, and it just arrived today!

It is HUGE compared to the Flipside 400. More thoughts to come once I load it up

Looking forward to your review/pics BenJohnson.