I had discussed doing this comparo with a couple of other members a few days ago. I enjoy the discussion these threads typically lead to. This is a quick and dirty comparison. A much better controlled comparison is at the digital picture I believe...
I had to do the test outside to get enough light to get respectable speeds. The problem was it was extremely windy and all my focus targets kept blowing around. I finally had to settle on a Allstate folder wedged in the fence (4-5m) and a shot of the neighbors house (~50m). The folder shots were taken from a tripod and the house shots were handheld with IS. I noticed the 100-400 shots were over a stop underexposed but the house shots were ok?? I shot all of them wide open with both lenses (f/5.6) and iso 100. Speeds on the handheld shots were fast enough to preclude camera movement as a problem.
Here are the native test shots. Crops to follow.



