I tend to avoid f22 and generally only ever go as small as f16 on very rare occasions.
Have a look at the test shots in this set here:
http://www.flickr.com …4/sets/72157623350445656/
and you can see as the aperture gets smaller the resulting images start to get a little softer - plus as the magnification increases you quickly have to start using wider and wider apertures to keep the sharpness (partly this is because the effective apertures have infact changed as part of the lenses construction and method of getting to the higher magnifications).
This is effectivly the work of diffraction and I think its a quick test that, whilst not terribly exciting, one can do in an evening and get an idea of the techincal limits of the lens and camera together. For some people f22 is fine for their desired level of quality and output - for others they might not want to close down that far and lose the overall detail and sharpness.
Tools of the trade: Canon 400D, Canon 7D, Canon 70-200mm f2.8 IS L M2, Sigma 120-300mm f2.8 OS, Canon MPE 65mm f2.8 macro, Sigma 150mm f2.8 macro, Tamron 24-70mm f2.4, Sigma 70mm f2.8 macro, Sigma 8-16mm f4.5-5.6, Raynox DCR 250, loads of teleconverters and a flashy thingy too
My flickr