For me, something like a quilt, like food, is best photographed 'in context'. Your first shot attempts this but is let down by flat lighting, low saturation/vibrance and messy arrangement of the quilt itself. It just looks like it's been tossed there.
Using the light from a window works well, provided you use it as directional light to create some shadow (and therefore depth and texture). Spend more time arranging the quilt in a stylish way (Mrs Wife should be able to help with that if she's a crafty person) and look out for unsightly creases and folds. Perhaps the quilt should be steamed first, to remove wrinkles?
If you haven't got studio lighting, window light and DIY reflectors such as simple sheets of white paper strategically positioned to control the shadows can work really well.
How are these quilts used? On a bed, as throws, or perhaps both? Whichever is the case, create a 'set' in the same way you would if it was an artsy movie, thinking not just about the quilt itself, and the lighting, but the typical use and then choose objects that will share the frame to convey the appropriate mood. Does your wife think her quilts are 'homely' or in some other style? Incorporate her vision into the 'set'.
Close-ups of details or stitching may be of interest to other quilters, showing your wife's skills or aesthetics, or potential buyers looking for high quality assembly.
5D3, 7D2, EF 16-35 f/2.8L, EF 24-70 f/2.8L II, EF 24-105 f/4L, EF 70-200 f/2.8L II, EF 100-400 f/4.5-5.6L II, EF 1.4x III, Sigma 150mm macro, Lumix LX100 plus a cupboard full of bags, tripods, flashes & stuff.