How about situations where you're shooting in bright daylight - hand held, very steady of course - at say, a 100mm equivalent focal length at a shutter speed of a 250th of a second? Is it better to shut the IS off for that particular shot?
That's not a particularly fast shutter speed for a 100mm lens--especially if it's really a heavy 70-200mm zoom. Did you know that hoary old thumbrule only applied to images enlarged no more than 10x?
Most people can't really hold a camera steady enough to use that thumbrule for images enlarged over 10X and people who can most often don't. Most of the "my lens is soft" complaints (when people are looking at 50x on their monitors) are really subtle camera shake.
Yes, use IS when you're handholding the lens.