I am a huge fan of Mountainsmith stuff. I have an Endeavor, and I like it a lot. It comes with their camera insert, which is removable so if you want to throw it in another bag you have that option. The insert is pretty nice. It has a bright yellow interior that makes it easy to see things, and it has a drawstring closure that you may or may not like. I like it because I can close it pretty tight, and it is pretty quick to open and close. The endeavor has a built in rain cover and laptop sleeve, which will probably hold a 15'' with relative ease. I can put my 13'' macbook pro in it with lots of room to spare. The insert will only hold one body and a couple of lenses, but the Endeavor is big enough to hold another body and lenses since the insert doesn't fill the bag up.