I've a well-worn LowePro CompuDaypack that I take everywhere, typically stuffed snug with an 11" Alienware m11x laptop; gripped 30D or 7D body; Tokina 11-16mm, Canon 24-105mm and Canon 100-400mm lenses. Taken it to Alaska, out west, Iceland, Southeast Asia, Southern Africa, just about everywhere. Great bag. Takes a beating.
I also have a larger Lowepro Pro Runner 350 AW. I intentionally chose it in lieu of the 450, even though the latter (as mentioned above) fits a gripped body far better, for carry-on airline travel. I planned to install the grips in country, then break down again for the flight home.
I'd love to use the 350 AW instead of the CompuDaypack to cart an extra body on photo vacations, and I do for road trips. Yet for longer travels, I'm always worried it won't meet specs and will be shunted into the checked area of the plane. So at the last minute, I invariably decide to stick with the proven CompuDaypack. It's still a great design, but it has no room for anything else.
Anyone have positive experiences to relate getting the 350 AW bag on flights? Has anyone had problems getting the 350 AW on a plane?
I'm heading for Kenya in the Fall, Virgin Atlantic, Dulles to Heathrow and Heathrow to Nairobi, on large Airbus A340-300/A340-600 planes. I wouldn't try it on Alaskan bush planes, but these are roomy cabins.