I'll just add to your question about detail.
If you convert from a Raw file to a full-size high-quality jpeg the compression that gets applied is minimal and you will have a full resolution pixel-wise so detail will be retained. I know the earlier poster said that "after a while" he noticed a difference but I doubt it is actual detail "missing" because all the pixels are reproduced in the jpeg. I'd be interested in seeing a 100% crop of the Raw and a jpeg that was converted at full size and high quality showing detail loss.
But when you resize an image during a conversion to a jpeg or tiff or whatever for, like you mentioned something like saving for the Web, you are throwing pixels away, and that means that finer detail will just disappear.
And, at lower quality settings you are eventually going to see other issues -- not detail loss as such but the lower the quality the more strange "artifacts" can be seen. This also happens when you save, open and re-save a jpeg multiple times -- eventually it can have a pretty ugly affect.
So, a good workflow is to do all you can in Raw, then, if you need to work on an image in Photoshop you can, and then if you have a project that you want to keep as a "working project" the "best practice" is to save as a tiff. At the point that you actually need to save for the Web, email, print, whatever is when you save the jpeg at the right size and quality for your intended use.